Directed nucleation assembly of DNA tile complexes for barcode-patterned lattices.

@article{Yan2003DirectedNA,
  title={Directed nucleation assembly of DNA tile complexes for barcode-patterned lattices.},
  author={Hao Yan and Thomas H. LaBean and Liping Feng and John H. Reif},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2003},
  volume={100 14},
  pages={8103-8}
}
The programmed self-assembly of patterned aperiodic molecular structures is a major challenge in nanotechnology and has numerous potential applications for nanofabrication of complex structures and useful devices. Here we report the construction of an aperiodic patterned DNA lattice (barcode lattice) by a self-assembly process of directed nucleation of DNA tiles around a scaffold DNA strand. The input DNA scaffold strand, constructed by ligation of shorter synthetic oligonucleotides, provides… CONTINUE READING

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