Direct vs. indirect effects of bombesin on pancreatic growth.

  title={Direct vs. indirect effects of bombesin on pancreatic growth.},
  author={R{\"u}diger Liehr and Stefan Rosewicz and Roger D Reidelberger and Travis E. Solomon},
  volume={46 Suppl 2},
Bombesin and its mammalian analogue gastrin-releasing peptide (GRP) have been reported to stimulate pancreatic growth. Whether this stimulatory effect is mediated through the release of regulatory peptides, in particular CCK, remains controversial. Since CCK is the most potent stimulant of pancreatic growth, it is a potential mediator of bombesin-induced pancreatic growth. On the other hand, there is evidence from in vitro studies, supporting a direct interaction of bombesin with receptors on… CONTINUE READING

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