Direct visualization of lipid domains in human skin stratum corneum's lipid membranes: effect of pH and temperature.

@article{Plasencia2007DirectVO,
  title={Direct visualization of lipid domains in human skin stratum corneum's lipid membranes: effect of pH and temperature.},
  author={In{\'e}s Plasencia and Lars P O Norl{\'e}n and Luis A. Bagatolli},
  journal={Biophysical journal},
  year={2007},
  volume={93 9},
  pages={
          3142-55
        }
}
The main function of skin is to serve as a physical barrier between the body and the environment. This barrier capacity is in turn a function of the physical state and structural organization of the stratum corneum extracellular lipid matrix. This lipid matrix is essentially composed of very long chain saturated ceramides, cholesterol, and free fatty acids. Three unsolved key questions are i), whether the stratum corneum extracellular lipid matrix is constituted by a single gel phase or by… CONTINUE READING
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