Direct visualization of cholecystokinin subtype2 receptors in rat central nervous system using anti-peptide antibodies.

@article{Mercer2000DirectVO,
  title={Direct visualization of cholecystokinin subtype2 receptors in rat central nervous system using anti-peptide antibodies.},
  author={Linda D Mercer and Viet Q Le and John D Nunan and Nicole M. Jones and Philip M. Beart},
  journal={Neuroscience letters},
  year={2000},
  volume={293 3},
  pages={167-70}
}
The cholecystokinin receptor, subtype 2 (CCK(2)R), is considered, based on receptor autoradiography, to be the predominant receptor for this peptide transmitter in the mammalian central nervous system. To directly visualize the CCK(2)R we utilized a convenient and sensitive immunohistochemical procedure using antipeptide receptor antibodies raised in rabbits against unique portions of the carboxyl tail and third intracellular loop of the CCK(2)R. Antibodies were characterized by ELISA and… CONTINUE READING
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