Direct repeats in the non-coding region of rabbit mitochondrial DNA. Involvement in the generation of intra- and inter-individual heterogeneity.

@article{Mignotte1990DirectRI,
  title={Direct repeats in the non-coding region of rabbit mitochondrial DNA. Involvement in the generation of intra- and inter-individual heterogeneity.},
  author={Françoise Mignotte and Monique Gu{\'e}ride and Anthony M. Champagne and J. C. Mounolou},
  journal={European journal of biochemistry},
  year={1990},
  volume={194 2},
  pages={561-71}
}
In rabbit we observed heteroplasmy at an exceptionally high level, the heterogeneity occurring within the non-coding region of the DNA. Mitochondrial DNA (mt DNA) was cloned in pBR322 and the nucleotide sequence analysis of an EcoRI-Hind III fragment encompassing the non-coding region revealed that although there are common features with other mammalian mtDNAs (termed large central-conserved-sequence block, conserved-sequence blocks 1, 2 and 3 and termination-associated elements) the non-coding… CONTINUE READING
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