Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1.

@article{Liu2006DirectRO,
  title={Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1.},
  author={Huarui Liu and Tamara J. Strauss and Malia B. Potts and Scott F Cameron},
  journal={Development},
  year={2006},
  volume={133 4},
  pages={641-50}
}
Hox genes are crucial determinants of cell fates and of body morphology of animals; mutations affecting these genes result in abnormal patterns of programmed cell death. How Hox genes regulate programmed cell death is an important and poorly understood aspect of normal development. In the nematode C. elegans, the Hox gene mab-5 is required for the… CONTINUE READING