Direct quantification of analyte concentration by resonant acoustic profiling.

@article{Godber2005DirectQO,
  title={Direct quantification of analyte concentration by resonant acoustic profiling.},
  author={Benjamin L J Godber and Kevin S. J. Thompson and Marian Rehak and Yıldız Bozkurt Uludağ and Sven Kelling and Alexander Sleptsov and Mark Frogley and Klaus Wiehler and Christopher Whalen and Matthew A. Cooper},
  journal={Clinical chemistry},
  year={2005},
  volume={51 10},
  pages={1962-72}
}
BACKGROUND Acoustic sensors that exploit resonating quartz crystals directly detect the binding of an analyte to a receptor. Applications include detection of bacteria, viruses, and oligonucleotides and measurement of myoglobin, interleukin 1beta (IL-1beta), and enzyme cofactors. METHODS Resonant Acoustic Profiling was combined with a microfluidic lateral flow device incorporating an internal reference control, stable linker chemistry, and immobilized receptors on a disposable sensor "chip… CONTINUE READING