Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes.
@article{Dodds2006DirectPI, title={Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes.}, author={P. Dodds and G. Lawrence and Ann-Maree Catanzariti and T. Teh and C. Wang and M. Ayliffe and B. Kobe and J. Ellis}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2006}, volume={103 23}, pages={ 8888-93 } }
Plant resistance proteins (R proteins) recognize corresponding pathogen avirulence (Avr) proteins either indirectly through detection of changes in their host protein targets or through direct R-Avr protein interaction. Although indirect recognition imposes selection against Avr effector function, pathogen effector molecules recognized through direct interaction may overcome resistance through sequence diversification rather than loss of function. Here we show that the flax rust fungus AvrL567… Expand
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- 2007
- 133
- PDF
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- 167
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References
SHOWING 1-10 OF 34 REFERENCES
Autoactive alleles of the flax L6 rust resistance gene induce non-race-specific rust resistance associated with the hypersensitive response.
- Biology, Medicine
- Molecular plant-microbe interactions : MPMI
- 2005
- 94
The Melampsora lini AvrL567 Avirulence Genes Are Expressed in Haustoria and Their Products Are Recognized inside Plant Cells
- Biology, Medicine
- The Plant Cell Online
- 2004
- 370
- PDF
Clusters of resistance genes in plants evolve by divergent selection and a birth-and-death process.
- Biology, Medicine
- Genome research
- 1998
- 920
- PDF
Physical interaction between RRS1-R, a protein conferring resistance to bacterial wilt, and PopP2, a type III effector targeted to the plant nucleus
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 2003
- 678
- PDF
Identification of Regions in Alleles of the Flax Rust Resistance Gene L That Determine Differences in Gene-for-Gene Specificity
- Biology, Medicine
- Plant Cell
- 1999
- 487
- PDF
Initiation of RPS2-Specified Disease Resistance in Arabidopsis Is Coupled to the AvrRpt2-Directed Elimination of RIN4
- Biology, Medicine
- Cell
- 2003
- 754
Natural selection for polymorphism in the disease resistance gene Rps2 of Arabidopsis thaliana.
- Biology, Medicine
- Genetics
- 2003
- 180
- PDF
Direct interaction of resistance gene and avirulence gene products confers rice blast resistance
- Biology, Medicine
- The EMBO journal
- 2000
- 1,084
Dynamics of disease resistance polymorphism at the Rpm1 locus of Arabidopsis
- Biology, Medicine
- Nature
- 1999
- 552
- PDF
Balancing selection favors guarding resistance proteins.
- Biology, Medicine
- Trends in plant science
- 2002
- 195