Direct prediction of NMR residual dipolar couplings from the primary sequence of unfolded proteins.

Abstract

Conformational analysis: an approach to the prediction of RDCs from disordered protein chains, integrating the effect of nearest neighbors and the alignment characteristics of the statistical coil, is reported. NMR residual dipolar couplings (RDC) are sensitive probes of conformational sampling in unfolded proteins.

DOI: 10.1002/anie.201206585

Cite this paper

@article{Huang2013DirectPO, title={Direct prediction of NMR residual dipolar couplings from the primary sequence of unfolded proteins.}, author={Jie-rong Huang and Val{\'e}ry Ozenne and Malene Ringkj\obing Jensen and Martin Blackledge}, journal={Angewandte Chemie}, year={2013}, volume={52 2}, pages={687-90} }