• Chemistry, Medicine
  • Published in Chemical communications 2003
  • DOI:10.1039/B309927J

Direct photomodulation of peptide backbone conformations.

@article{Zhao2003DirectPO,
  title={Direct photomodulation of peptide backbone conformations.},
  author={Jianzhang Zhao and Dirk Wildemann and Mario Jakob and Carolyn Vargas and Cordelia Schiene-Fischer},
  journal={Chemical communications},
  year={2003},
  volume={22},
  pages={
          2810-1
        }
}
Significant photoswitching ability is found for secondary thioxopeptide bonds and can be used for the photomodulation of the backbone conformation of peptides or proteins. 

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Synthesis and diuretic activities of pseudoproline-containing analogues of the insect kinin core pentapeptide.

A photoswitchable thioxopeptide bond facilitates the conformation-activity correlation study of insect kinin.