Direct observation of motion of single F-actin filaments in the presence of myosin

@article{Yanagida1984DirectOO,
  title={Direct observation of motion of single F-actin filaments in the presence of myosin},
  author={Toshio Yanagida and Michiyuki Nakase and Katsumi Nishiyama and Fumio Oosawa},
  journal={Nature},
  year={1984},
  volume={307},
  pages={58-60}
}
Actin is found in almost all kinds of non-muscle cells where it is thought to have an important role in cell motility. A proper understanding of that role will only be possible when reliable in vitro systems are available for investigating the interaction of cellular actin and myosin. A start has been made on several systems1–4, most recently by Sheetz and Spudich who demonstrated unidirectional movement of HMM-coated beads along F-actin cables on arrays of chloroplasts exposed by dissection of… CONTINUE READING

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