Direct observation of hematopoietic progenitor chimerism in fetal freemartin cattle

BACKGROUND Cattle twins are well known as blood chimeras. However, chimerism in the actual hematopoietic progenitor compartment has not been directly investigated. Here, we analyzed fetal liver of chimeric freemartin cattle by combining a new anti-bovine CD34 antibody and Y-chromosome specific in situ hybridization. RESULTS Bull-derived CD34+ cells were… CONTINUE READING