Direct observation of DNA rotation during transcription by Escherichia coli RNA polymerase


Helical filaments driven by linear molecular motors are anticipated to rotate around their axis, but rotation consistent with the helical pitch has not been observed. 14S dynein and non-claret disjunctional protein (ncd) rotated a microtubule more efficiently than expected for its helical pitch, and myosin rotated an actin filament only poorly. For DNA… (More)
DOI: 10.1038/35051126

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