Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease.

@article{Burgos2007DirectMP,
  title={Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease.},
  author={Juan Miguel Burgos and Jaime M. Altcheh and Margarita Maria Catalina Bisio and Tom{\'a}s Duffy and Helder Magno Silva Valadares and Mar{\'i}a Elena Seidenstein and Romina Valeria Piccinali and Jorge Marcelo Freitas and Mariano Jorge Levin and Liliana Macchi and Andr{\'e}a Mara Macedo and H{\'e}ctor Leon Freilij and Alejandro G Schijman},
  journal={International journal for parasitology},
  year={2007},
  volume={37 12},
  pages={1319-27}
}
Congenital transmission of Trypanosoma cruzi may occur in some or all the gestations from a T. cruzi-infected mother. Variable rates of congenital transmission have been reported in different geographical areas where different parasitic strains predominate, suggesting that parasitic genotypes might play a role in the risk of congenital transmission. Moreover, in cases of transmission it is unknown if the whole maternal T. cruzi population or certain clones are preferentially transmitted by the… CONTINUE READING
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