Direct mechano-stress sensitivity of TRPM7 channel.

@article{Numata2007DirectMS,
  title={Direct mechano-stress sensitivity of TRPM7 channel.},
  author={Tomohiro Numata and Takahiro Shimizu and Yasunobu Okada},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2007},
  volume={19 1-4},
  pages={
          1-8
        }
}
It has recently been shown that shear stress augments the heterologously expressed TRPM7 channel activity by exocytosis-mediated incorporation of TRPM7 into the plasma membrane. On the other hand, our recent study has shown that the TRPM7-like channel endogenously expressed in HeLa cells is activated by membrane expansion induced by membrane stretch or osmotic cell swelling. Thus, the present study was aimed at exploring the possibility that the heterogously expressed TRPM7 channel is activated… CONTINUE READING

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