Direct measurement of the transfer rate of chloroplast DNA into the nucleus

@article{Huang2003DirectMO,
  title={Direct measurement of the transfer rate of chloroplast DNA into the nucleus},
  author={Chun Yao Huang and Michael A. Ayliffe and Jeremy N. Timmis},
  journal={Nature},
  year={2003},
  volume={422},
  pages={72-76}
}
Gene transfer from the chloroplast to the nucleus has occurred over evolutionary time. Functional gene establishment in the nucleus is rare, but DNA transfer without functionality is presumably more frequent. Here, we measured directly the transfer rate of chloroplast DNA (cpDNA) into the nucleus of tobacco plants (Nicotiana tabacum). To visualize this process, a nucleus-specific neomycin phosphotransferase gene (neoSTLS2) was integrated into the chloroplast genome, and the transfer of cpDNA to… CONTINUE READING
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