Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate.

Abstract

We have used the membrane-localized calcium probe fura-piperazine-C12H25 (FFP-18) to examine cytosolic calcium concentrations in a volume close to the plasmalemma. Although promotion of axon outgrowth by cell adhesion molecules requires extracellular calcium and is correlated with an opening of plasmalemmal channels, conventional indicators cannot detect a… (More)

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Cite this paper

@article{Chadborn2002DirectMO, title={Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate.}, author={Neil H. Chadborn and Britta Johanna Eickholt and Patrick Doherty and Stephen R. Bolsover}, journal={The European journal of neuroscience}, year={2002}, volume={15 12}, pages={1891-8} }