Direct mass spectrometric screening of antibiotics from bacterial surfaces using liquid extraction surface analysis.


RATIONALE There is a need to find new antibiotic agents to fight resistant pathogenic bacteria. To search successfully for novel antibiotics from bacteria cultivated under diverse conditions, we need a fast and cost-effective screening method. METHODS A combination of Liquid Extraction Surface Analysis (LESA), automated chip-based nanoelectrospray… (More)
DOI: 10.1002/rcm.6365


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