Direct isolation of neural stem cells in the adult hippocampus after traumatic brain injury.

@article{Gao2008DirectIO,
  title={Direct isolation of neural stem cells in the adult hippocampus after traumatic brain injury.},
  author={Xiang Gao and Grigori Enikolopov and Jinhui Chen},
  journal={Journal of neurotrauma},
  year={2008},
  volume={25 8},
  pages={985-95}
}
Recently, we have manipulated endogenous neural stem/progenitor cells (NSCs) in situ in the adult mouse to undergo neurogenesis and anatomic circuit re-formation de novo in the neocortex, where it does not normally occur, by using a highly targeted brain injury model. However, how the NSCs respond to injury in the adult mouse brain is poorly understood. While studying the molecular mechanisms that regulate NSC fates after brain injury, it is important to develop a strategy to identify NSCs in… CONTINUE READING

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