Direct isolation of flavonoids from plants using ultra-small anatase TiO₂ nanoparticles.

@article{Kurepa2014DirectIO,
  title={Direct isolation of flavonoids from plants using ultra-small anatase TiO₂ nanoparticles.},
  author={Jasmina Kurepa and Ryo Nakabayashi and Tatjana Paunesku and Makoto Suzuki and Kazuki Saito and Gayle Woloschak and Jan A. Smalle},
  journal={The Plant journal : for cell and molecular biology},
  year={2014},
  volume={77 3},
  pages={443-53}
}
Surface functionalization of nanoparticles has become an important tool for in vivo delivery of bioactive agents to their target sites. Here we describe the reverse strategy, nanoharvesting, in which nanoparticles are used as a tool to isolate bioactive compounds from living cells. Anatase TiO₂ nanoparticles smaller than 20 nm form strong bonds with molecules bearing enediol and especially catechol groups. We show that these nanoparticles enter plant cells, conjugate enediol and catechol group… CONTINUE READING
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