Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters.

@article{Sawamoto2001DirectIO,
  title={Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters.},
  author={Kazunobu Sawamoto and Atsuyo Yamamoto and Ayano Kawaguchi and Masahiro Yamaguchi and Kensaku Mori and Steven A Goldman and Hideyuki Okano},
  journal={Journal of neuroscience research},
  year={2001},
  volume={65 3},
  pages={220-7}
}
Many tissues arise from pluripotent stem cells through cell-type specification and maturation. In the bone marrow, primitive stem cells generate all the different types of blood cells via the sequential differentiation of increasingly committed progenitor cells. Cell-surface markers that clearly distinguish stem cells, restricted progenitors, and differentiated progeny have enabled researchers to isolate these cells and to study the regulatory mechanisms of hematopoiesis. Neuronal… CONTINUE READING
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