Direct genomic selection

@article{Bashiardes2005DirectGS,
  title={Direct genomic selection},
  author={S. Bashiardes and Rose A Veile and C. Helms and E. Mardis and A. Bowcock and M. Lovett},
  journal={Nature Methods},
  year={2005},
  volume={2},
  pages={63-69}
}
Searching for genetic variants and mutations that underlie human diseases, both simple and complex, presents particular challenges. In the case of complex diseases, these searches generally result in a single nucleotide polymorphism (SNP), or set of SNPs, associated with disease risk. Frequently, these SNPs lie outside the gene coding regions1,2. One is thus left in a quandary: do the detected SNPs represent the only genetic variation in the region or are there additional variants that might… Expand
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