Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo.

@article{Nita1996DirectGD,
  title={Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo.},
  author={I. D. Nita and Steven C. Ghivizzani and Joanna Galea-Lauri and G. Bandara and Helga I. Georgescu and Peter D. Robbins and Christopher H. Evans},
  journal={Arthritis and rheumatism},
  year={1996},
  volume={39 5},
  pages={
          820-8
        }
}
OBJECTIVE To assess the abilities of various vectors to transfer genes to the synovial lining of joints. METHODS Vectors derived from retrovirus, adenovirus, and herpes simplex virus as well as cationic liposomes and naked plasmid DNA were evaluated. Each construct contained the lac Z marker gene; and one retroviral construct, and one plasmid also contained a gene encoding human interleukin-1 receptor antagonist. Gene expression was under the control of the human cytomegalovirus promoter in… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 62 CITATIONS, ESTIMATED 56% COVERAGE

Gene therapy of arthritis

VIEW 1 EXCERPT
CITES BACKGROUND

Arthritis gene therapy and its tortuous path into the clinic.

  • Translational research : the journal of laboratory and clinical medicine
  • 2013

FILTER CITATIONS BY YEAR

1997
2018

CITATION STATISTICS

  • 1 Highly Influenced Citations