Direct evidence that growth cones pull

  title={Direct evidence that growth cones pull},
  author={P. Lamoureux and Robert E. Buxbaum and Steven R. Heidemann},
THERE is controversy over whether axonal elongation is the result of a pulling growth cone and the role of tension in axonal elongationl-4. Earlier in this decade, the consensus was that axons or neurites elongated from tension generated by forward motility of the growth cone5,6. It was presumed that contractile filopodia were the source of the tension moving the growth cone7,8. But this view was challenged by experiments showing that neurites elongate, albeit abnormally, in the presence of… CONTINUE READING