Direct evidence of sudden rise in fetal corticoids late in human gestation

  title={Direct evidence of sudden rise in fetal corticoids late in human gestation},
  author={Montserrat deM Fencl and Robert J. Stillman and Jane Cohen and Dan Tulchinsky},
Glucocorticoids accelerate fetal lung maturation in all mammals studied1, and in some species, such as goat and sheep, concentrations of fetal cortisol increase sharply before term, bringing about a train of events leading to parturition2. Studies of cortisol in the umbilical cord blood have revealed no such increase at the end of human pregnancy. But information obtained in that way is difficult to interpret because much of the fetal cortisol is of maternal origin3,4 and its concentration, if… CONTINUE READING


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