Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960

@article{Worobey2008DirectEO,
  title={Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960},
  author={Michael Worobey and Marlea Gemmel and Dirk E. Teuwen and Tamara S. Haselkorn and Kevin J. Kunstman and Michael Bunce and Jean-Jacques Muyembe and Jean-Marie Mpolesha Kabongo and Rapha{\"e}l Mbowa Kalengayi and Eric A. E. Van Marck and Marcus Thomas Pius Gilbert and Steven M. Wolinsky},
  journal={Nature},
  year={2008},
  volume={455},
  pages={661-664}
}
Human immunodeficiency virus type 1 (HIV-1) sequences that pre-date the recognition of AIDS are critical to defining the time of origin and the timescale of virus evolution. A viral sequence from 1959 (ZR59) is the oldest known HIV-1 infection. Other historically documented sequences, important calibration points to convert evolutionary distance into time, are lacking, however; ZR59 is the only one sampled before 1976. Here we report the amplification and characterization of viral sequences… CONTINUE READING
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References

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Global HIV/AIDS Medicine (eds Volberding

  • M. Worobey
  • (Saunders Elsevier,
  • 2008

Highresolution molecular epidemiology and evolutionary history of HIV-1 subtypes in Albania

  • M. Salemi, T. de Oliveira, M. Ciccozzi, G. Rezza, M. M. Goodenow
  • PLoS ONE 3,
  • 2008

The emergence of HIV-1 in the Americas and beyond

  • Gilbert, P M.T.
  • Proc. Natl Acad. Sci. USA 104,
  • 2007

The isolation of nucleic acids from fixed, paraffin-embedded tissues — which methods are useful when

  • Gilbert, P M.T.
  • PLoS ONE 2,
  • 2007

Characterization of the 1918 influenza virus polymerase genes

  • Taubenberger, K J.
  • Nature 437,
  • 2005

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