Direct evidence of bacterial biofilms in otitis media.

  • J. Post
  • Published 2001 in The Laryngoscope


OBJECTIVES/HYPOTHESIS Bacteriologic studies of otitis media with effusion (OME) using highly sensitive techniques of molecular biology such as the polymerase chain reaction have demonstrated that traditional culturing methods are inadequate to detect many viable bacteria present in OME. The presence of pathogens attached to the middle-ear mucosa as a… (More)


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