Direct evidence for susceptibility genes for type 2 diabetes on mouse chromosomes 11 and 14

Abstract

Diabetogenic loci for type 2 diabetes have been mapped to mouse chromosome (Chr) 11 and 14 in the Nagoya–Shibata–Yasuda (NSY) mouse, an animal model of type 2 diabetes. We aimed to obtain direct evidence of these genes on each chromosome and to clarify their function and interaction in conferring susceptibility to type 2 diabetes. We established three… (More)
DOI: 10.1007/s00125-010-1737-5

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