Direct evidence for coherent low velocity axonal transport of mitochondria

@article{Miller2006DirectEF,
  title={Direct evidence for coherent low velocity axonal transport of mitochondria},
  author={Kyle E. Miller and Michael P Sheetz},
  journal={The Journal of Cell Biology},
  year={2006},
  volume={173},
  pages={373 - 381}
}
Axonal growth depends on axonal transport. We report the first global analysis of mitochondrial transport during axonal growth and pauses. In the proximal axon, we found that docked mitochondria attached to the cytoskeletal framework that were stationary relative to the substrate and fast axonal transport fully accounted for mitochondrial transport. In the distal axon, we found both fast mitochondrial transport and a coherent slow transport of the mitochondria docked to the axonal framework… CONTINUE READING

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