Direct enantiomeric separation of cathinone and one major metabolite on cellobiohydrolase (CBH-I) chiral stationary phase.

@article{AboulEnein1997DirectES,
  title={Direct enantiomeric separation of cathinone and one major metabolite on cellobiohydrolase (CBH-I) chiral stationary phase.},
  author={Hassan Y Aboul-Enein and Vincent Serignese},
  journal={Biomedical chromatography : BMC},
  year={1997},
  volume={11 1},
  pages={47-9}
}
A direct, isocratic high-performance liquid chromatographic (HPLC) method is described for the enantiomeric separation of racemic cathinone and one of its metabolites (+/-)-norephedrine, on a protein-based chiral stationary phase (CSP), cellobiohydrolase, known as CBH-I, under reversed-phase conditions. It was determined that the S-(-)-enantiomer eluted… CONTINUE READING