• DOI:10.1016/0304-3940(95)11445-3
Corpus ID: 54394931

Direct effects of the anabolic/androgenic steroids, stanozolol and 17α-methyltestosterone, on benzodiazepine binding to the γ-aminobutyric acidA receptor

@article{Masonis1995DirectEO,
  title={Direct effects of the anabolic/androgenic steroids, stanozolol and 17α-methyltestosterone, on benzodiazepine binding to the γ-aminobutyric acidA receptor},
  author={A. E. Masonis and M. Mccarthy},
  journal={Neuroscience Letters},
  year={1995},
  volume={189},
  pages={35-38}
}

A. E. Masonis, M. Mccarthy

Published 1995

Chemistry

Neuroscience Letters

Abstract Various exogenous and endogenous steroids have been demonstrated to have both enhancing and inhibiting effects on ligand binding to the γ-aminobutyric acid A receptor (GABA A receptor) in previous studies. In the present study we have explored the possibility that an additional class of synthetic steroidal compounds, anabolic/androgenic steroids (AAS), mediate some of their CNS effects through direct interaction with the GABA A receptor. At micromolar concentrations, two AAS… CONTINUE READING

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