Direct effects of medroxyprogesterone acetate, danazol, and leuprolide acetate on endometrial stromal cell proliferation in vitro.

@article{Surrey1992DirectEO,
  title={Direct effects of medroxyprogesterone acetate, danazol, and leuprolide acetate on endometrial stromal cell proliferation in vitro.},
  author={Eric S. Surrey and Jukka Halme},
  journal={Fertility and sterility},
  year={1992},
  volume={58 2},
  pages={273-8}
}
OBJECTIVE To assess the direct effects of three endometriosis chemotherapeutic agents (medroxyprogesterone acetate [MPA], danazol, and leuprolide acetate [LA]) on endometrial cell proliferation. DESIGN Analysis of cell proliferation in vitro. SETTING Proliferative phase endometrial stromal cells isolated from biopsy specimens and grown in short-term culture served as a model for stromal components of endometriotic implants. PATIENTS Biopsies obtained from volunteers with regular cycles… CONTINUE READING

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