Direct effects of glimepiride on protein expression of cardiac glucose transporters.

@article{Eckel1996DirectEO,
  title={Direct effects of glimepiride on protein expression of cardiac glucose transporters.},
  author={J. Eckel},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={1996},
  volume={28 9},
  pages={
          508-11
        }
}
  • J. Eckel
  • Published 1996
  • Biology, Medicine
  • Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Freshly isolated rat cardiomyocytes, primary cultured cardiomyocytes and the cardiac cell line H9c2 were used to elucidate acute and chronic effects of the sulfonylurea glimepiride on basal and insulin-stimulated glucose uptake and on the expression of the transporter isoforms GLUT1 and GLUT4. Initial rates of 3-O-methylglucose transport in freshly isolated cardiocytes were not acutely affected by glimepiride (100 microM) both in the absence or presence of insulin (10(-7)M). Cells were then… Expand
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