Direct conversion of alcohols to acetals and H(2) catalyzed by an acridine-based ruthenium pincer complex.

@article{Gunanathan2009DirectCO,
  title={Direct conversion of alcohols to acetals and H(2) catalyzed by an acridine-based ruthenium pincer complex.},
  author={C. Gunanathan and L. Shimon and D. Milstein},
  journal={Journal of the American Chemical Society},
  year={2009},
  volume={131 9},
  pages={
          3146-7
        }
}
  • C. Gunanathan, L. Shimon, D. Milstein
  • Published 2009
  • Chemistry, Medicine
  • Journal of the American Chemical Society
  • The crystallographically characterized ruthenium complex RuHCl(A-(i)Pr-PNP)(CO) (1) [A-(i)Pr-PNP = 4,5-bis-(diisopropylphosphinomethyl)acridine], which bears a nonplanar acridine moiety, catalyzes in a neutral medium the transformation of primary alcohols to the corresponding acetals with the liberation of H(2). In the presence of base, complex 1 catalyzes the dehydrogenative coupling of alcohols to form esters. Acetal formation may involve hemiacetal dehydration to form an enol ether followed… CONTINUE READING
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