Direct conversion of alcohols to α-chloro aldehydes and α-chloro ketones.

Abstract

Direct conversion of primary and secondary alcohols into the corresponding α-chloro aldehydes and α-chloro ketones using trichloroisocyanuric acid, serving both as stoichiometric oxidant and α-halogenating reagent, is reported. For primary alcohols, TEMPO has to be added as an oxidation catalyst, and for the transformation of secondary alcohols (TEMPO-free… (More)
DOI: 10.1021/ol5024568

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Cite this paper

@article{Jing2014DirectCO, title={Direct conversion of alcohols to α-chloro aldehydes and α-chloro ketones.}, author={Yuanyuan Jing and Constantin G Daniliuc and Armido Studer}, journal={Organic letters}, year={2014}, volume={16 18}, pages={4932-5} }