Direct binding of low molecular weight haptens to ELISA plates.

@article{Hofstetter1997DirectBO,
  title={Direct binding of low molecular weight haptens to ELISA plates.},
  author={Oliver Hofstetter and Heike Hofstetter and D Then and Volker Schurig and Bernard S. Green},
  journal={Journal of immunological methods},
  year={1997},
  volume={210 1},
  pages={89-92}
}
Immobilization of low molecular weight haptens in ELISA usually involves their coupling to protein molecules or covalent binding to the solid phase. In this study we demonstrate that it is possible to directly bind the hapten p-aminophenylalanine to gamma-irradiated polystyrene microtiter plates for the detection of antibodies that stereospecifically… CONTINUE READING