Direct aqueous synthesis of non-protected glycosyl sulfoxides; weak inhibitory activity against glycosidases.


A flavinium catalyst, in conjunction with hydrogen peroxide as stoichiometric oxidant, allowed the aqueous conversion of non-protected thioglycosides into the corresponding glycosyl sulfoxides. These glycosyl sulfoxides displayed only very weak inhibitory activity against corresponding glycosidases. 
DOI: 10.1016/j.carres.2015.06.003

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