Direct aqueous determination of glyphosate and related compounds by liquid chromatography/tandem mass spectrometry using reversed-phase and weak anion-exchange mixed-mode column.

@article{Hao2011DirectAD,
  title={Direct aqueous determination of glyphosate and related compounds by liquid chromatography/tandem mass spectrometry using reversed-phase and weak anion-exchange mixed-mode column.},
  author={Chunyan Hao and D. II. Morse and Franca Morra and Xiaoming Zhao and Puhai Yang and Brian Nunn},
  journal={Journal of chromatography. A},
  year={2011},
  volume={1218 33},
  pages={5638-43}
}
Analysis of the broad-spectrum herbicide glyphosate and its related compounds is quite challenging. Tedious and time-consuming derivatization is often required for these substances due to their high polarity, high water solubility, low volatility and molecular structure which lacks either a chromophore or fluorophore. A novel liquid chromatography/tandem mass spectrometry (LC/MS-MS) method has been developed for the determination of glyphosate, aminomethylphosphonic acid (AMPA) and glufosinate… CONTINUE READING
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