Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency.

@article{Kutsch2002DirectAQ,
  title={Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency.},
  author={Olaf Kutsch and Etty Nadia Benveniste and George M. Shaw and David N Levy},
  journal={Journal of virology},
  year={2002},
  volume={76 17},
  pages={8776-86}
}
The ability of human immunodeficiency virus type 1 (HIV-1) to establish latent infections in cells has received renewed attention owing to the failure of highly active antiretroviral therapy to eradicate HIV-1 in vivo. Despite much study, the molecular bases of HIV-1 latency and reactivation are incompletely understood. Research on HIV-1 latency would benefit from a model system that is amenable to rapid and efficient analysis and through which compounds capable of regulating HIV-1 reactivation… CONTINUE READING

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