Direct and indirect protection of right ventricular function by estrogen in an experimental model of pulmonary arterial hypertension.

Abstract

Pulmonary arterial hypertension (PAH) results in right ventricular (RV) dysfunction and failure. Paradoxically, women are more frequently diagnosed with PAH but have better RV systolic function and survival rates than men. The mechanisms by which sex differences alter PAH outcomes remain unknown. Here, we sought to study the role of estrogen in RV… (More)
DOI: 10.1152/ajpheart.00758.2013

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Cite this paper

@article{Liu2014DirectAI, title={Direct and indirect protection of right ventricular function by estrogen in an experimental model of pulmonary arterial hypertension.}, author={Aiping Liu and D. Schreier and Lian Tian and Jens Eickhoff and Zhijie Wang and Timothy A. Hacker and Naomi C. Chesler}, journal={American journal of physiology. Heart and circulatory physiology}, year={2014}, volume={307 3}, pages={H273-83} }