Direct and indirect antioxidant properties of inducers of cytoprotective proteins.

@article{DinkovaKostova2008DirectAI,
  title={Direct and indirect antioxidant properties of inducers of cytoprotective proteins.},
  author={Albena T Dinkova-Kostova and Paul Talalay},
  journal={Molecular nutrition & food research},
  year={2008},
  volume={52 Suppl 1},
  pages={S128-38}
}
Cellular protection against oxidative and electrophile toxicities is provided by two types of small-molecule antioxidants: (i) direct antioxidants, which are redox active, short-lived, are sacrificed in the process of their antioxidant actions and need to be replenished or regenerated, and may evoke pro-oxidant effects; and (ii) indirect antioxidants, that may or may not be redox active. Indirect antioxidants activate the Keap1/Nrf2/ARE pathway resulting in transcriptional induction of a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 179 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 113 references

Curcu - min activates human glutathione Stransferase P 1 expression through antioxidant response element

  • T. Nishinaka, Y. Ichijo, M. Ito, M. Kimura
  • Toxicol . Lett .
  • 2007

Free Radicals in Biology and Medicine, Fourth Edition

  • B. Halliwell, J.M.C. Gutteridge
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…