Direct and indirect T cell priming by dendritic cell vaccines.

Abstract

The mechanisms by which dendritic cell (DC) vaccines prime host T cells in vivo was analyzed. Mice were immunized with syngeneic bone marrow-derived DC and as surrogate antigen beta-galactosidase (beta-gal) was used. DC either pulsed with peptide, loaded with beta-gal antigen or gene-modified induced beta-gal-specific cytotoxic T lymphocytes (CTL) and… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.