Direct Oral Anticoagulants in Emergency Trauma Admissions.

@article{Maegele2016DirectOA,
  title={Direct Oral Anticoagulants in Emergency Trauma Admissions.},
  author={Marc G. Maegele and Oliver Grottke and Herbert Sch{\"o}chl and Oliver A Sakowitz and Michael Spannagl and Juergen Koscielny},
  journal={Deutsches Arzteblatt international},
  year={2016},
  volume={113 35-36},
  pages={
          575-82
        }
}
BACKGROUND Direct (non-vitamin-K-dependent) oral anticoagulants (DOAC) are given as an alternative to vitamin K antagonists (VKA) to prevent stroke and embolic disease in patients with atrial fibrillation that is not due to pathology of the heart valves. Fatal hemorrhage is rarer when DOACs are given (nonvalvular atrial fibrillation: odds ratio [OR] 0.68; 95% confidence interval [95% CI: 0.48; 0.96], and venous thromboembolism: OR 0.54; [0.22; 1.32]). 48% of emergency trauma patients need an… CONTINUE READING