Direct Loading and Tunable Release of Antibiotics from Polyelectrolyte Multilayers To Reduce Bacterial Adhesion and Biofilm Formation.

@article{Wang2016DirectLA,
  title={Direct Loading and Tunable Release of Antibiotics from Polyelectrolyte Multilayers To Reduce Bacterial Adhesion and Biofilm Formation.},
  author={Bailiang Wang and Tingwei Jin and Qingwen Xu and Huihua Liu and Zi Ye and Hao Chen},
  journal={Bioconjugate chemistry},
  year={2016},
  volume={27 5},
  pages={1305-13}
}
Bacteria adhesion on the surface of biomaterials and following biofilm formation are important problems in biomedical applications. The charged antibiotics with small molar mass can hardly deposit alternately with polymers into multilayered films to load the drug. Herein, the (poly(acrylic acid)-gentamicin/poly(ethylenimine))n ((PAA-GS/PEI)n) multilayer… CONTINUE READING