Corpus ID: 214657946

Direct Demonstration of Alterations in the Microcirculation of the Hamster during and following Renal Hypertension

  title={Direct Demonstration of Alterations in the Microcirculation of the Hamster during and following Renal Hypertension},
  author={P. Joseph and Gilmore and L. William and Joyner},
The effects of norepinephrine (NE) on arterioles and venules and measured arteriolar wall (W) to lumen (L) ratios in the hamster cheek pouch were compared during the development of hypertension (HT) during sustained HT and following antihypertensive therapy. After the determination of baseline blood pressures in 25 hamsters, the cheek pouch microcirculation was evaluated (day O). NE (0.5-1,000 ng) was applied in 3.35-/zl volumes to arterioles and venules. An image shearer was used to measure W… Expand

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Analysis of Changes in Reactivity of Rabbit Arteries and Veins Two Weeks after Induction of Hypertension by Coarctation of the Abdominal Aorta
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Electrogenesis of Increased Norepinephrine Sensitivity of Arterial Vascular Muscle in Hypertension
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It appears that changes in sensitivity as well as altered vascular geometry are important in the production of vascular hyperresponsiveness in the spontaneously hypertensive rat. Expand
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Importance of Adaptive Changes in Vascular Design for Establishment of Primary Hypertension, Studied in Man and in Spontaneously Hypertensive Rats
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  • S. Baez
  • Materials Science, Medicine
  • Circulation research
  • 1969
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