Direct DNA hybridization detection based on the oligonucleotide-functionalized conductive polymer.

@article{Lee2001DirectDH,
  title={Direct DNA hybridization detection based on the oligonucleotide-functionalized conductive polymer.},
  author={Tsz Yan Lee and Yoon Bo Shim},
  journal={Analytical chemistry},
  year={2001},
  volume={73 22},
  pages={5629-32}
}
Electrochemical methods for DNA hybridization detection have many advantages that are very fast to detect hybridization and can be directly applied for a portable DNA sensor. In this paper, an electrochemical method to directly detect DNA hybridization was developed on the basis of a new conductive polymer, which was polymerized on the glassy carbon electrode with a terthiophene monomer having a carboxyl group (3'-carboxyl-5,2',5',2"-terthiophene). The ss-DNA probe was made by chemically… CONTINUE READING
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