• Corpus ID: 101129241

Direct Base-to-Base Transitions in ssDNA Revealed by Tip-Enhanced Raman Scattering

@article{Lin2016DirectBT,
  title={Direct Base-to-Base Transitions in ssDNA Revealed by Tip-Enhanced Raman Scattering},
  author={Xiumei Lin and Tanja Deckert-Gaudig and Prabha Singh and Michel Siegmann and Stephan Kupfer and Zhenglong Zhang and Stefanie Grafe and Volker Deckert},
  journal={arXiv: Chemical Physics},
  year={2016}
}
In the present contribution, specifically designed single-stranded DNA (ssDNA) sequences composed of adenine and cytosine were used as nanometric rulers to target the maximum achievable spatial resolution of tip-enhanced Raman spectroscopy (TERS) under ambient conditions. By stepping along a strand with a TERS tip, the obtained spectra allowed for a clear spectral discrimination including conformational information of the nucleobases, and even sharp adenine-cytosine transitions were detected… 

Figures and Tables from this paper

Laser spectroscopic technique for direct identification of a single virus I: FASTER CARS

TLDR
The aim of the present paper is to show that identification of individual virus particles in clinical sample materials quickly and reliably is near at hand by combining the spatial resolution of atomic force microscopy and the spectral resolution of coherent Raman spectroscopy.

Facilitated tip-enhanced Raman scattering by focused gap-plasmon hybridization

Tip-enhanced Raman scattering (TERS) spectroscopy is a nondestructive and label-free molecular detection approach that provides high sensitivity and nanoscale spatial resolution. Therefore, it has

Tip-enhanced Raman spectroscopy: principles, practice, and applications to nanospectroscopic imaging of 2D materials

TLDR
This review provides a summary of methods to study 2D monolayers and an overview of TERS, followed by an introduction to the current state-of-the-art and theoretical understanding the spatial resolution in TERS experiments.

Tip-enhanced Raman spectroscopy - from early developments to recent advances.

TLDR
The development of this still-young technique, from early experiments to recent achievements concerning inorganic, organic, and biological materials, is addressed and an assessment of the frontiers and new concepts of TERS, which aim towards rendering it a general and widely applicable technique that combines the highest possible lateral resolution and extreme sensitivity are provided.