Diphosphorylation of the myosin regulatory light chain enhances the tension acting on stress fibers in fibroblasts.

Abstract

Regulation of the contractile force is crucial for cell migration, cell proliferation, and maintenance of cell morphology. Phosphorylation of the myosin II regulatory light chain (MRLC) is involved in these processes. To show whether the diphosphorylation of MRLC increases the tension acting on stress fibers, changes in the stiffness of fibroblasts… (More)

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