Diphenyl Ditelluride Intoxication Triggers Histological Changes in Liver, Kidney, and Lung of Mice

@article{Luz2015DiphenylDI,
  title={Diphenyl Ditelluride Intoxication Triggers Histological Changes in Liver, Kidney, and Lung of Mice},
  author={S. C. A. da Luz and M. Daubermann and G. Thom{\'e} and M. M. dos Santos and A. Ramos and Gerson Torres Salazar and J. D. da Rocha and N. V. Barbosa},
  journal={Analytical Cellular Pathology (Amsterdam)},
  year={2015},
  volume={2015}
}
  • S. C. A. da Luz, M. Daubermann, +5 authors N. V. Barbosa
  • Published 2015
  • Medicine
  • Analytical Cellular Pathology (Amsterdam)
  • Tellurium compounds may be cytotoxic to different cells types. Thus, this work evaluated the effect of diphenyl ditelluride ((PhTe)2), an organotellurium commonly used in organic synthesis, on the morphology of liver, kidney, and lung. Adult mice were acutely (a subcutaneous single dose: 250 μmol/kg) or subchronically (one daily subcutaneous dose: 10 or 50 μmol/kg for 7 and 14 days) exposed to (PhTe)2. Afterwards, the histological analyses of liver, kidney, and lungs were performed. Liver… CONTINUE READING
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