Diphenhydramine modulates cytokines and induces apoptosis in experimental acute pancreatitis.

Abstract

In this study, we investigated the therapeutic potential of diphenhydramine (DPH), a H(1) receptor antagonist, on taurocholate-induced acute pancreatitis and the underlying mechanisms involved. Rats were randomly divided into sham-operated, model, DPH-treated, octreotide-treated and the DPH plus octreotide combination therapy groups (n = 30 per group… (More)
DOI: 10.1358/mf.2010.32.5.1428739

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